Pharmaceutical Science & Engineering

Research in this area has been concentrated on developing a fundamental understanding of pharmaceutical manufacturing with an emphasis on particulate processing.

Research areas include:

  1. The development of modeling tools to design, simulate and optimize the integration of different unit operations for the efficient production of pharmaceuticals.  
  2. The development of an understanding of fundamental phenomena controlling properties of composite materials. The approaches used combine theory, atomistic simulations of nano and microstructures, continuum-based simulations of meso and macrostructures, and experiments.
  3. The development of fundamental understanding of the hydrodynamics and heat and mass transfer in fluid-particle and granular flows/processes and applying this understanding to improve the design and operation of pharmaceutical processes.
  4. The design, modeling and operation of continuous powder manufacturing systems for pharmaceutical production.
  5. The material and powder characterization including nano- and micro-structural characterization of solid dosage forms.
  6. The development of an understanding of powder handling operations relevant to pharmaceutical production including blending, sampling, granulation, compaction, drying and milling.

Faculty in Pharmaceutical Science & Engineering Research:  Glasser, Ierapetritou, Muzzio, Ramachandran, Tomassone

Research on the granular flow regimes observed in bladed mixers and we are developing scale-up rules (Benjamin Glasser) Fundamental understanding of particulate systems with emphasis in pharmaceutical applications (Fernando Muzzio)
Continuous Pharmaceutical Advanced Manufacturing Laboratory (CpAML)