Research in this area has been concentrated on developing a fundamental understanding of pharmaceutical manufacturing with an emphasis on particulate processing.
Research areas include:
- The development of modeling tools to design, simulate and optimize the integration of different unit operations for the efficient production of pharmaceuticals.
- The development of an understanding of fundamental phenomena controlling properties of composite materials. The approaches used combine theory, atomistic simulations of nano and microstructures, continuum-based simulations of meso and macrostructures, and experiments.
- The development of fundamental understanding of the hydrodynamics and heat and mass transfer in fluid-particle and granular flows/processes and applying this understanding to improve the design and operation of pharmaceutical processes.
- The design, modeling and operation of continuous powder manufacturing systems for pharmaceutical production.
- The material and powder characterization including nano- and micro-structural characterization of solid dosage forms.
- The development of an understanding of powder handling operations relevant to pharmaceutical production including blending, sampling, granulation, compaction, drying and milling.
Faculty in Pharmaceutical Science & Engineering Research: Glasser, Ierapetritou, Muzzio, Ramachandran, Tomassone
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| Research on the granular flow regimes observed in bladed mixers and we are developing scale-up rules (Benjamin Glasser) | Fundamental understanding of particulate systems with emphasis in pharmaceutical applications (Fernando Muzzio) |
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| Continuous Pharmaceutical Advanced Manufacturing Laboratory (CpAML) |